The main theme of the film as reported earlier is said to be based on an English movie, Derailed. Let's take a quick look at the story of the movie.

The story is about an executive from a multi national company, whose financial status is very strong, married with a beautiful wife, and has a 6 years old daughter.

His daughter suffers from a perennial diabetic problem with insulin injections to be administered everyday. Due to this, major portion of his earnings goes for the medical treatment, and hospitalization of the child.

And moreover, the intimate relationship between the husband and wife starts to deteriorate due to their worry and concern for their child. At this juncture, another woman enters into the life of the hero. What starts as a simple offer in buying his rail ticket, blossoms into an illicit relationship. A clandestine meet in a hotel room takes a twist when an unknown man barges in, robs them and rapes her.

Later on, the same man starts visiting his home and starts blackmailing him every week and takes money from him without the knowledge of his wife and daughter.

He looses all his money, including the savings that he had made for his one and only daughters' medical treatment. After loosing everything, his wife, comes to know the extramarital relationship of her husband, eventually she decides to go and live separately along with her daughter.

At this sad state of affairs, the hero, comes to know a mind blowing truth accidentally that the criminal, who is ransacking money from him, is none other than the illicit lover's husband, and both of them plotted together and extracted the money from him.

The climax of the story is how the hero recovers money from the kidnappers, and gives it to the hospitalization expenses of his beloved daughter.

For Pachaikili Muthucharam, Sarathkumar plays the lead role as the hero, Mumbai model Andrea acts as his wife; the ailing daughter is replaced by a son. Jyothika's role is that of the woman who entices Sarathkumar to enter into an extra marital affair. Milind Suman acts as the kidnapper, who plots along with his wife Jyothika against Sarathkumar and extracts money from him.

Now what has to be seen is how much truth is there in the rumors that Gautham's version is inspired by Derailed. Will Jyothika still remain the negative role in story? Will Tamil movie goers accept her as a villain?